Furan drugs, also known as nitrofurans, are a class of chemical synthetic drugs found later than sulfa drugs. It has a broad-spectrum antibacterial effect, inhibits Gram-positive and negative cocci and bacilli in vitro, and can be sterilized at a high concentration, but has poor antibacterial activity against Proteus and Pseudomonas. The characteristics of furan drugs are that bacteria are not easy to produce drug resistance and drug resistance, and they are not resistant to sulfa drugs and antibiotics. Its antibacterial effect is also unaffected by pus and tissue breakdown. Therefore, in recent years, there has been a trend of expanding application in the prevention and treatment of bacterial diseases of fish and shrimp.
Commonly used are:
Nitrofuran (yellow powder)
Properties: This product is a lemon yellow crystalline powder, no odor, slightly bitter. The color gradually changes in daylight. It is slightly soluble in water and slightly soluble in alcohol.
Control objects and methods of use:
(1) Use 1-2 grams per 100 kilograms of fish to make a bait to feed, and feed a course of treatment every half month, every 3 days for one course of treatment, to prevent enteritis;
(2) It can prevent red skin, rotten cockroaches and enteritis with a 50,000-centrifuge body bath for 10 minutes.
Also known as 痢特灵 Yellow crystalline powder, tasteless. Slightly soluble in water and ethanol. When the light color becomes darker, it can be dissolved in the case of alkali.
For the prevention and treatment of a variety of fish, shrimp bacterial diseases, oral or medicated baths, such as enteritis, rotten fins, rotten tails, etc.
A good medicine for the treatment of fish head cavity disease, has a killing effect on Gram-negative bacteria, broad-spectrum antibacterial, and can be used with fish by Vaseline.
Alias: arganmycin, oxytetracycline
Gray-yellow crystalline powder, odorless, melting point 181-182 ° C. It is stable in the air and darkens in strong sunlight. Hard to dissolve in water, slightly soluble in ethanol, soluble in dilute hydrochloric acid solution. Its saturated aqueous solution was pH 6.6. Rapid destruction in an alkali hydroxide solution. The basic properties of oxytetracycline hydrochloride are the same as oxytetracycline, hygroscopic, soluble in water, and the pH of a 1% aqueous solution is about 2.5. The antibacterial spectrum of oxytetracycline is the same as that of tetracycline. Generally, in addition to Gram-negative and positive, it also plays a role in rickettsia and some large viruses and protozoa. Oral administration or medicated bath. Note that due to the wide application of this product, in recent years, the resistance of bacteria to oxytetracycline has gradually increased, and the curative effect has decreased. Secondly, according to the relevant data, it can be combined with calcium and magnesium to reduce the antibacterial activity.
Control objects and methods of use: (1) Add 400 mg of oxytetracycline per kg of beverage to make a bait for 6 days to cure Edwards disease; (2) dip the fish body with 25 ppm of the drug solution Hours, can cure white-headed white-mouth disease and rotten tail disease
White or yellowish crystalline powder, odorless, slightly hygroscopic. Slightly soluble in water, soluble in ethanol, chloroform, ether and acetone. Its saturated aqueous solution has a pH of 8 to 10.5 and is quite stable in a neutral aqueous solution below 5 ° C. It can be stored for several weeks. After several weeks at room temperature, it is destroyed. When the pH is lower than 5, it is rapidly destroyed. The antibacterial spectrum of this product is similar to that of penicillin G, mainly resistant to Gram-positive bacteria. Poor activity against Gram-negative bacteria. Used for fish and shrimp diseases caused by Gram-positive bacteria.
Control objects and methods of use: (1) Use 100 mg of this product per kilogram of fish on the first day (1 million units per gram), and use 50 mg of bait per day for the second and sixth days. Feed for 1 week to treat enteritis. (2) uniformly dissolve erythromycin (containing 1 million units per gram) into the aquarium to achieve a water concentration of 0.07 ppm; the next day, the erythromycin powder is mixed into the beverage for feeding, which can cure bacterial rot disease .
The fish that are injured on the body can be sterilized and sterilized. Because it contains petrolatum, it can be attached to the fish.
Soluble in water, methanol, almost insoluble in ether, chloroform, acetone. Stable to acid, easy to fail in alkaline solution. According to the determination of the minimum inhibitory concentration of this product on the pathogen of fish sarcoidosis, Pasteurella is 0.04-0.08 μg / ml, showing that this product has a strong antibacterial. Ampicillin is a broad-spectrum semi-synthetic penicillin.
Penicillin sodium or penicillin potassium: antibiotics, used to prevent infection in broodstock after birth, intramuscular or intraperitoneal injection, 100,000 to 200,000 units / tail.
White or yellowish white powder or injection, odorless, bitter, hygroscopic. Soluble in water, slightly soluble in ethanol, insoluble in chloroform, ether. 25% aqueous solution pH 4.5-7.0, stable, can be stored for 2-3 weeks at room temperature, can be stored in the refrigerator for one year. In case of acid, alkali, heat and oxidant, reducing agent, etc., it is easy to fail. This product becomes pale yellow after being placed, generally does not affect the quality. Streptomycin has a broad spectrum of antibacterial activity and is effective against a variety of Gram-negative bacteria, and is also effective against some Gram-positive bacteria, but not as good as penicillin. In the prevention and treatment of fish and shrimp diseases, there are medicated baths, injections and the like. Note that this product has no batch number as a prescription for aquaculture at home and abroad, and has been developed as a veterinary drug.
Streptomycin sulfate is an antibiotic medicine used to prevent broodstock infection, intramuscular or intraperitoneal injection, 100,000 to 200,000 units/tail.
White to yellowish, fine needle-like or flaky crystal, odorless, bitter, melting point 149-153 ° C. Slightly soluble in water, soluble in organic solvents such as ethanol, saturated aqueous solution is neutral. Stable in neutral and medium acidity solutions, aqueous solution of chloramphenicol at pH 2-9 is stable whether placed under boiling or room temperature conditions. Chloramphenicol is a broad-spectrum antibiotic that inhibits both Gram-negative and positive bacteria and is also effective against rickettsia. The medicine has good control effects on vibriosis, pseudomonas disease and aerobic disease of marine fish and shrimp, and is used as a sprinkling and medicated bath in addition to oral administration (made as a bait). Wait. note. Regular use can produce resistance and affect body growth.
It is an antibiotic medicine, broad-spectrum antibacterial, and has inhibitory effects on Gram-positive and Gram-negative bacteria. It is used to treat vibriosis and acne. The drug weight per kilogram of fish is 0.025-0.05 grams, the first dose is 0.05 grams, and then half-quantity is maintained for 3 to 5 days.
Chloramphenicol eye drops
Used to give blindfold fish anti-inflammatory treatments have special effects
Function and Indications: Antibiotics. Used for Gram-negative and positive bacterial infections to promote inflammation recovery, can promote post-natal rehabilitation of broodstock and prevent bacterial infections in the beading of the brood.
Black-purple, triangular prismatic crystals or granules. Odorless, sweet and astringent. Stable in the air, soluble in water. This product is a strong oxidant. When it encounters organic matter, it releases new ecological oxygen. Its mechanism of action is to exert its bactericidal action by oxidizing the active groups in the bacteria (such as sulfur-based enzymes). This product also has a killing effect on parasitic protozoa. The medicated bath or the whole pool is also used for disinfection of seed pools, hatcheries and tools.
Chemical dyeing agent, mainly for the treatment of water mildew, whitehead, white mouth, etc., a small amount of use has the role of prevention and treatment, low toxicity.
Dyestuff sterilization and insect repellent for controlling water mold, rotten rot, rotten fin disease and parasitic diseases. Dipping at a concentration of 1 to 5 mg / liter for 1 hour can prevent rotten rot and rotten fin disease; immersion in a concentration of 67 mg / liter for 5 to 10 minutes can treat water mold; use 1% malachite The green solution is applied to the broodstock wound to prevent infection.
Also known as biliary or blue sputum, it is a blue crystalline powder, slightly transparent, metallic, and weathering in dry air. Soluble in water, slightly soluble in ethanol, slowly soluble in glycerin. The aqueous solution is acidic.
Copper sulphate and bleaching powder mixture, immersed in the concentration of 8 ~ 10 mg / liter for 20 ~ 30 minutes, can prevent rotten rickets, red skin disease and cockroach whipworm, fish Bo worm, worms, tube worms and other native Animal disease. Sprinkle copper sulphate and ferrous sulfate to make the water body a concentration of 0.7 mg / liter, which can kill the snails and snails in the water body, prevent the occurrence of trematode and blood schistosomiasis; It can prevent or treat mild bacterial and parasitic fish diseases.
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